Fare Guide

Estimated lowest fares found within 7 days

Cheapest Airline Allegiant Air LLC

The cheapest airline(s) flying from Des Moines to San Diego is Allegiant Air LLC.

  • Allegiant Air LLC Allegiant Air LLC
  • American Airlines American Airlines
  • United Airlines United Airlines
  • Frontier Airlines Frontier Airlines
  • Delta Air Lines Delta Air Lines
  • Alaska Airlines Alaska Airlines
Cheapest Month July

Travel Period: June 2024 - May 2025

The cheapest month(s) to fly from Des Moines to San Diego is July.

  • Jun 2024
  • Jul 2024
  • Aug 2024
  • Sep 2024
  • Oct 2024
  • Nov 2024
  • Dec 2024
  • Jan 2025
  • Feb 2025
  • Mar 2025
  • Apr 2025
  • May 2025
Cheapest Day of the Week Friday

The cheapest day(s) of the week to fly from Des Moines to San Diego is Friday.

  • Sun Sunday
  • Mon Monday
  • Tue Tuesday
  • Wed Wednesday
  • Thu Thursday
  • Fri Friday
  • Sat Saturday
Cheapest Time 2pm

The cheapest time of the day to fly from Des Moines to San Diego is in the afternoon.

Early Morning 12:01am - 06:00am
Morning 6:01am - 12:00pm
Afternoon 12:01pm - 6:00pm
Evening 6:01pm to 12:00am
12am
6am
12pm
6pm

Flight Schedules

Last Updated: Thu, 2 May, 2024

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  • Availability
    • M
    • T
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    • T
    • F
    • S
    • S
  • 14:55 - 20:00
    DSM - SAN
  • 14:55 (DSM)Des Moines Airport
  • 20:00 (SAN)San Diego International Airport
  • Southwest Airlines (WN 5238)Boeing 737 700
  • 7h 05m
  • Direct
    • -
    • -
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    • S
  • Boeing 737 700

Connecting Flights

  • 06:05 - 07:10
    DSM - STL
    10:05 - 11:55
    STL - SAN
  • 06:05 (DSM)Des Moines Airport
    10:05 (STL)St Louis Lambert Intl Airport
  • 07:10 (STL)St Louis Lambert Intl Airport
    11:55 (SAN)San Diego International Airport
  • Southwest Airlines (WN 5858)Boeing 737 700
    Southwest Airlines (WN 4676)Boeing 737 800
  • 7h 50m (2h 55m)
  • STL Saint Louis 2h 55m
    • -
    • -
    • -
    • -
    • -
    • S
    • -
  • 07:15 - 08:05
    DSM - DEN
    12:15 - 13:35
    DEN - SAN
  • 07:15 (DSM)Des Moines Airport
    12:15 (DEN)Denver Intl Airport
  • 08:05 (DEN)Denver Intl Airport
    13:35 (SAN)San Diego International Airport
  • Southwest Airlines (WN 5220)Boeing 737 700
    Southwest Airlines (WN 3147)Boeing 737 Max 8 Passenger
  • 8h 20m (4h 10m)
  • DEN Denver 4h 10m
    • -
    • -
    • -
    • -
    • -
    • S
    • -
  • 12:00 - 13:10
    PHX - SAN
    07:15 - 08:05
    DSM - DEN
  • 12:00 (PHX)Phoenix Sky Harbor Intl Airport
    07:15 (DSM)Des Moines Airport
  • 13:10 (SAN)San Diego International Airport
    08:05 (DEN)Denver Intl Airport
  • Southwest Airlines (WN 444)Boeing 737 700
    Southwest Airlines (WN 5220)Boeing 737 700
  • 7h 55m (3h)
  • SAN San Diego 3h
    • -
    • -
    • -
    • -
    • -
    • S
    • -
  • 07:15 - 08:05
    DSM - DEN
    09:25 - 10:45
    DEN - SAN
  • 07:15 (DSM)Des Moines Airport
    09:25 (DEN)Denver Intl Airport
  • 08:05 (DEN)Denver Intl Airport
    10:45 (SAN)San Diego International Airport
  • Southwest Airlines (WN 5220)Boeing 737 700
    Southwest Airlines (WN 2662)Boeing 737 Max 8 Passenger
  • 5h 30m (1h 20m)
  • DEN Denver 1h 20m
    • -
    • -
    • -
    • -
    • -
    • S
    • -
  • 11:05 - 12:15
    LAS - SAN
    07:15 - 08:05
    DSM - DEN
  • 11:05 (LAS)Las Vegas McCarran International Airport
    07:15 (DSM)Des Moines Airport
  • 12:15 (SAN)San Diego International Airport
    08:05 (DEN)Denver Intl Airport
  • Southwest Airlines (WN 2544)Boeing 737 700
    Southwest Airlines (WN 5220)Boeing 737 700
  • 7h (2h 05m)
  • SAN San Diego 2h 05m
    • -
    • -
    • -
    • -
    • -
    • S
    • -
  • 07:45 - 08:40
    DSM - DEN
    13:35 - 15:00
    DEN - SAN
  • 07:45 (DSM)Des Moines Airport
    13:35 (DEN)Denver Intl Airport
  • 08:40 (DEN)Denver Intl Airport
    15:00 (SAN)San Diego International Airport
  • Southwest Airlines (WN 5220)Boeing 737 700
    Southwest Airlines (WN 4085)Boeing 737 Max 8 Passenger
  • 9h 15m (4h 55m)
  • DEN Denver 4h 55m
    • -
    • T
    • W
    • -
    • -
    • -
    • -
  • 07:45 - 08:40
    DSM - DEN
    10:40 - 12:05
    DEN - SAN
  • 07:45 (DSM)Des Moines Airport
    10:40 (DEN)Denver Intl Airport
  • 08:40 (DEN)Denver Intl Airport
    12:05 (SAN)San Diego International Airport
  • Southwest Airlines (WN 5220)Boeing 737 700
    Southwest Airlines (WN 2949)Boeing 737 800
  • 6h 20m (2h)
  • DEN Denver 2h
    • -
    • T
    • W
    • -
    • -
    • -
    • -
  • 11:10 - 12:20
    PHX - SAN
    07:45 - 08:40
    DSM - DEN
  • 11:10 (PHX)Phoenix Sky Harbor Intl Airport
    07:45 (DSM)Des Moines Airport
  • 12:20 (SAN)San Diego International Airport
    08:40 (DEN)Denver Intl Airport
  • Southwest Airlines (WN 3966)Boeing 737 800
    Southwest Airlines (WN 5220)Boeing 737 700
  • 6h 35m (1h 35m)
  • SAN San Diego 1h 35m
    • -
    • T
    • W
    • -
    • -
    • -
    • -
  • 11:55 - 12:50
    ABQ - SAN
    07:45 - 08:40
    DSM - DEN
  • 11:55 (ABQ)Albuquerque Airport
    07:45 (DSM)Des Moines Airport
  • 12:50 (SAN)San Diego International Airport
    08:40 (DEN)Denver Intl Airport
  • Southwest Airlines (WN 4521)Boeing 737 700
    Southwest Airlines (WN 5220)Boeing 737 700
  • 7h 05m (2h)
  • SAN San Diego 2h
    • -
    • T
    • W
    • -
    • -
    • -
    • -
  • 13:05 - 14:15
    PHX - SAN
    08:35 - 09:30
    DSM - DEN
  • 13:05 (PHX)Phoenix Sky Harbor Intl Airport
    08:35 (DSM)Des Moines Airport
  • 14:15 (SAN)San Diego International Airport
    09:30 (DEN)Denver Intl Airport
  • Southwest Airlines (WN 1980)Boeing 737 Max 8 Passenger
    Southwest Airlines (WN 1141)Boeing 737 700
  • 7h 40m (2h 40m)
  • SAN San Diego 2h 40m
    • -
    • -
    • -
    • -
    • -
    • -
    • S
  • 08:35 - 09:30
    DSM - DEN
    14:20 - 15:45
    DEN - SAN
  • 08:35 (DSM)Des Moines Airport
    14:20 (DEN)Denver Intl Airport
  • 09:30 (DEN)Denver Intl Airport
    15:45 (SAN)San Diego International Airport
  • Southwest Airlines (WN 1141)Boeing 737 700
    Southwest Airlines (WN 1309)Boeing 737 700
  • 9h 10m (4h 50m)
  • DEN Denver 4h 50m
    • -
    • -
    • -
    • -
    • -
    • -
    • S
  • 13:10 - 14:20
    LAS - SAN
    08:35 - 09:30
    DSM - DEN
  • 13:10 (LAS)Las Vegas McCarran International Airport
    08:35 (DSM)Des Moines Airport
  • 14:20 (SAN)San Diego International Airport
    09:30 (DEN)Denver Intl Airport
  • Southwest Airlines (WN 1232)Boeing 737 700
    Southwest Airlines (WN 1141)Boeing 737 700
  • 7h 45m (2h 40m)
  • SAN San Diego 2h 40m
    • -
    • -
    • -
    • -
    • -
    • -
    • S
  • 08:35 - 09:30
    DSM - DEN
    12:10 - 13:30
    DEN - SAN
  • 08:35 (DSM)Des Moines Airport
    12:10 (DEN)Denver Intl Airport
  • 09:30 (DEN)Denver Intl Airport
    13:30 (SAN)San Diego International Airport
  • Southwest Airlines (WN 1141)Boeing 737 700
    Southwest Airlines (WN 4085)Boeing 737 700
  • 6h 55m (2h 40m)
  • DEN Denver 2h 40m
    • -
    • -
    • -
    • -
    • -
    • -
    • S
  • 11:50 - 13:00
    DSM - LAS
    14:30 - 15:50
    LAS - SAN
  • 11:50 (DSM)Des Moines Airport
    14:30 (LAS)Las Vegas McCarran International Airport
  • 13:00 (LAS)Las Vegas McCarran International Airport
    15:50 (SAN)San Diego International Airport
  • Southwest Airlines (WN 2714)Boeing 737 700
    Southwest Airlines (WN 1924)Boeing 737 Max 8 Passenger
  • 6h (1h 30m)
  • LAS Las Vegas 1h 30m
    • -
    • -
    • -
    • -
    • -
    • S
    • -
  • 16:30 - 17:45
    PHX - SAN
    12:15 - 13:25
    DSM - LAS
  • 16:30 (PHX)Phoenix Sky Harbor Intl Airport
    12:15 (DSM)Des Moines Airport
  • 17:45 (SAN)San Diego International Airport
    13:25 (LAS)Las Vegas McCarran International Airport
  • Southwest Airlines (WN 954)Boeing 737 700
    Southwest Airlines (WN 2714)Boeing 737 700
  • 7h 30m (1h 45m)
  • SAN San Diego 1h 45m
    • -
    • -
    • -
    • -
    • -
    • -
    • S
  • 12:15 - 13:25
    DSM - LAS
    16:50 - 18:00
    LAS - SAN
  • 12:15 (DSM)Des Moines Airport
    16:50 (LAS)Las Vegas McCarran International Airport
  • 13:25 (LAS)Las Vegas McCarran International Airport
    18:00 (SAN)San Diego International Airport
  • Southwest Airlines (WN 2714)Boeing 737 700
    Southwest Airlines (WN 3501)Boeing 737 700
  • 7h 45m (3h 25m)
  • LAS Las Vegas 3h 25m
    • -
    • -
    • -
    • -
    • -
    • -
    • S
  • 12:20 - 13:35
    DSM - LAS
    17:15 - 18:30
    LAS - SAN
  • 12:20 (DSM)Des Moines Airport
    17:15 (LAS)Las Vegas McCarran International Airport
  • 13:35 (LAS)Las Vegas McCarran International Airport
    18:30 (SAN)San Diego International Airport
  • Southwest Airlines (WN 2714)Boeing 737 700
    Southwest Airlines (WN 1924)Boeing 737 700
  • 8h 10m (3h 40m)
  • LAS Las Vegas 3h 40m
    • -
    • T
    • W
    • -
    • -
    • -
    • -
  • 12:40 - 13:55
    DSM - LAS
    16:50 - 18:05
    LAS - SAN
  • 12:40 (DSM)Des Moines Airport
    16:50 (LAS)Las Vegas McCarran International Airport
  • 13:55 (LAS)Las Vegas McCarran International Airport
    18:05 (SAN)San Diego International Airport
  • Southwest Airlines (WN 2714)Boeing 737 800
    Southwest Airlines (WN 4104)Boeing 737 700
  • 7h 25m (2h 55m)
  • LAS Las Vegas 2h 55m
    • M
    • -
    • -
    • T
    • F
    • -
    • -
  • 17:15 - 18:25
    PHX - SAN
    12:40 - 13:55
    DSM - LAS
  • 17:15 (PHX)Phoenix Sky Harbor Intl Airport
    12:40 (DSM)Des Moines Airport
  • 18:25 (SAN)San Diego International Airport
    13:55 (LAS)Las Vegas McCarran International Airport
  • Southwest Airlines (WN 1844)Boeing 737 Max 8 Passenger
    Southwest Airlines (WN 2714)Boeing 737 800
  • 7h 45m (2h)
  • SAN San Diego 2h
    • M
    • -
    • -
    • T
    • F
    • -
    • -
  • 14:55 - 15:50
    DSM - DEN
    20:00 - 21:25
    DEN - SAN
  • 14:55 (DSM)Des Moines Airport
    20:00 (DEN)Denver Intl Airport
  • 15:50 (DEN)Denver Intl Airport
    21:25 (SAN)San Diego International Airport
  • Southwest Airlines (WN 3022)Boeing 737 Max 8 Passenger
    Southwest Airlines (WN 4088)Boeing 737 Max 8 Passenger
  • 8h 30m (4h 10m)
  • DEN Denver 4h 10m
    • -
    • -
    • -
    • -
    • -
    • S
    • -
  • 19:05 - 20:35
    SMF - SAN
    14:55 - 15:50
    DSM - DEN
  • 19:05 (SMF)Sacramento International Airport
    14:55 (DSM)Des Moines Airport
  • 20:35 (SAN)San Diego International Airport
    15:50 (DEN)Denver Intl Airport
  • Southwest Airlines (WN 4172)Boeing 737 700
    Southwest Airlines (WN 3022)Boeing 737 Max 8 Passenger
  • 7h 40m (1h 40m)
  • SAN San Diego 1h 40m
    • -
    • -
    • -
    • -
    • -
    • S
    • -
  • 14:55 - 15:50
    DSM - DEN
    17:25 - 18:50
    DEN - SAN
  • 14:55 (DSM)Des Moines Airport
    17:25 (DEN)Denver Intl Airport
  • 15:50 (DEN)Denver Intl Airport
    18:50 (SAN)San Diego International Airport
  • Southwest Airlines (WN 3022)Boeing 737 Max 8 Passenger
    Southwest Airlines (WN 369)Boeing 737 700
  • 5h 55m (1h 35m)
  • DEN Denver 1h 35m
    • -
    • -
    • -
    • -
    • -
    • S
    • -
  • 14:55 - 15:50
    DSM - DEN
    17:40 - 19:05
    DEN - SAN
  • 14:55 (DSM)Des Moines Airport
    17:40 (DEN)Denver Intl Airport
  • 15:50 (DEN)Denver Intl Airport
    19:05 (SAN)San Diego International Airport
  • Southwest Airlines (WN 5238)Boeing 737 700
    Southwest Airlines (WN 701)Boeing 737 800
  • 6h 10m (1h 50m)
  • DEN Denver 1h 50m
    • -
    • -
    • -
    • -
    • -
    • -
    • S
  • 14:55 - 15:50
    DSM - DEN
    19:45 - 21:10
    DEN - SAN
  • 14:55 (DSM)Des Moines Airport
    19:45 (DEN)Denver Intl Airport
  • 15:50 (DEN)Denver Intl Airport
    21:10 (SAN)San Diego International Airport
  • Southwest Airlines (WN 5238)Boeing 737 700
    Southwest Airlines (WN 4110)Boeing 737 700
  • 8h 15m (3h 55m)
  • DEN Denver 3h 55m
    • -
    • -
    • -
    • -
    • -
    • -
    • S
  • 15:25 - 16:20
    DSM - DEN
    17:35 - 19:00
    DEN - SAN
  • 15:25 (DSM)Des Moines Airport
    17:35 (DEN)Denver Intl Airport
  • 16:20 (DEN)Denver Intl Airport
    19:00 (SAN)San Diego International Airport
  • Southwest Airlines (WN 1595)Boeing 737 700
    Southwest Airlines (WN 4087)Boeing 737 800
  • 5h 35m (1h 15m)
  • DEN Denver 1h 15m
    • M
    • -
    • -
    • T
    • F
    • -
    • -
  • 15:25 - 17:55
    DSM - PHX
    19:25 - 20:35
    PHX - SAN
  • 15:25 (DSM)Des Moines Airport
    19:25 (PHX)Phoenix Sky Harbor Intl Airport
  • 17:55 (PHX)Phoenix Sky Harbor Intl Airport
    20:35 (SAN)San Diego International Airport
  • Southwest Airlines (WN 1595)Boeing 737 700
    Southwest Airlines (WN 1519)Boeing 737 700
  • 7h 10m (1h 30m)
  • PHX Phoenix 1h 30m
    • M
    • -
    • -
    • T
    • F
    • -
    • -
  • 15:25 - 16:20
    DSM - DEN
    18:55 - 20:20
    DEN - SAN
  • 15:25 (DSM)Des Moines Airport
    18:55 (DEN)Denver Intl Airport
  • 16:20 (DEN)Denver Intl Airport
    20:20 (SAN)San Diego International Airport
  • Southwest Airlines (WN 1595)Boeing 737 700
    Southwest Airlines (WN 4088)Boeing 737 700
  • 6h 55m (2h 35m)
  • DEN Denver 2h 35m
    • M
    • -
    • -
    • T
    • F
    • -
    • -
  • 16:10 - 17:05
    DSM - DEN
    21:00 - 22:20
    DEN - SAN
  • 16:10 (DSM)Des Moines Airport
    21:00 (DEN)Denver Intl Airport
  • 17:05 (DEN)Denver Intl Airport
    22:20 (SAN)San Diego International Airport
  • Southwest Airlines (WN 3022)Boeing 737 Max 8 Passenger
    Southwest Airlines (WN 3936)Boeing 737 700
  • 8h 10m (3h 55m)
  • DEN Denver 3h 55m
    • -
    • T
    • W
    • -
    • -
    • -
    • -
  • 20:35 - 22:05
    OAK - SAN
    16:10 - 17:05
    DSM - DEN
  • 20:35 (OAK)Oakland International Airport
    16:10 (DSM)Des Moines Airport
  • 22:05 (SAN)San Diego International Airport
    17:05 (DEN)Denver Intl Airport
  • Southwest Airlines (WN 5056)Boeing 737 700
    Southwest Airlines (WN 3022)Boeing 737 Max 8 Passenger
  • 7h 55m (1h 45m)
  • SAN San Diego 1h 45m
    • -
    • T
    • W
    • -
    • -
    • -
    • -
  • 20:40 - 21:50
    LAS - SAN
    16:10 - 17:05
    DSM - DEN
  • 20:40 (LAS)Las Vegas McCarran International Airport
    16:10 (DSM)Des Moines Airport
  • 21:50 (SAN)San Diego International Airport
    17:05 (DEN)Denver Intl Airport
  • Southwest Airlines (WN 5953)Boeing 737 700
    Southwest Airlines (WN 3022)Boeing 737 Max 8 Passenger
  • 7h 40m (2h 35m)
  • SAN San Diego 2h 35m
    • -
    • T
    • W
    • -
    • -
    • -
    • -
  • 16:10 - 17:05
    DSM - DEN
    18:30 - 20:00
    DEN - SAN
  • 16:10 (DSM)Des Moines Airport
    18:30 (DEN)Denver Intl Airport
  • 17:05 (DEN)Denver Intl Airport
    20:00 (SAN)San Diego International Airport
  • Southwest Airlines (WN 3022)Boeing 737 Max 8 Passenger
    Southwest Airlines (WN 4088)Boeing 737 800
  • 5h 50m (1h 25m)
  • DEN Denver 1h 25m
    • -
    • T
    • W
    • -
    • -
    • -
    • -
  • 21:25 - 22:50
    DEN - SAN
    17:30 - 18:30
    DSM - STL
  • 21:25 (DEN)Denver Intl Airport
    17:30 (DSM)Des Moines Airport
  • 22:50 (SAN)San Diego International Airport
    18:30 (STL)St Louis Lambert Intl Airport
  • Southwest Airlines (WN 3936)Boeing 737 700
    Southwest Airlines (WN 2785)Boeing 737 800
  • 7h 20m (1h 35m)
  • SAN San Diego 1h 35m
    • M
    • -
    • -
    • T
    • F
    • -
    • -
No Schedules Sorry, there are no schedules matching your filters. Try removing one. reset
What’s the fastest flight time from Des Moines to San Diego?

The fastest flight time for direct flights from Des Moines to San Diego is 7 hours 5 minutes. Check latest flight schedules & prices on Wego.

How far is San Diego from Des Moines?

The flight distance between Des Moines and San Diego is 2299km. Check all available flights on Wego.

When is the earliest and latest flight of the day?

The earliest flight of the day departs at 06:05. The last flight of the day departs at 06:05. See the full list of flight times on Wego.

How many airlines offer direct flights from Des Moines to San Diego?

There are 1 airlines that offer direct flights from Des Moines to San Diego. Find out the list of airlines on Wego.